Explain the importance of the cytochrome P-450 enzyme in toxicant biotransformation. 

Question 1

 

Identify the methods by which toxicants enter the body. Provide a brief description and at least two examples of each. 

Your response should be at least 250 words in length. You are required to use at least your textbook as source material for your response. All sources used, including the textbook, must be referenced; paraphrased and quoted material must have accompanying citations.

 

Question 2

 

List and describe the factors that affect the distribution of a toxicant in the body. 

 

Your response should be at least 250 words in length. You are required to use at least your textbook as source material for your response. All sources used, including the textbook, must be referenced; paraphrased and quoted material must have accompanying citations.

 

Question 3

 

Explain the importance of the cytochrome P-450 enzyme in toxicant biotransformation. 

 

Your response should be at least 250 words in length. You are required to use at least your textbook as source material for your response. All sources used, including the textbook, must be referenced; paraphrased and quoted material must have accompanying citations.

 

Question 4

 

Explain the importance of phase 2 reactions. Include three examples of phase two reactions and a brief discussion for each.

 

Your response should be at least 250 words in length. You are required to use at least your textbook as source material for your response. All sources used, including the textbook, must be referenced; paraphrased and quoted material must have accompanying citations.