What are the differences between the mechanism of action of ACTH and cortisol on target cells? 

  1. The dexamethasone test involves the administration of a  synthetic glucocorticoid ( i.e., cortisol). Knowing what you do about  negative feedback mechanisms, how might this test be used to assess  pituitary function?
  2. Describe how the steroid hormones, like cortisol, are  metabolized in the body. What are the advantages of using a 24-hour urine test to measure this hormone?
  3. Protein-based and steroid-based hormones trigger  cellular responses in different ways. What are the differences between the mechanism of action of ACTH and cortisol on target cells?